Immunological responsiveness of neonatal A/J mice to isotypic determinants of syngeneic IgE.
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منابع مشابه
Immunological responsiveness of neonatal A/J mice to isotypic determinants of syngeneic IgE
We have previously shown that adult A/J mice produce high titers of anti-IgE with isotypic or idiotypic specificities in response to challenge with a conjugate of KLH with syngeneic monoclonal IgE. Thus, B cells that can synthesize anti-IgE are present in the mice. Adult mice are unresponsive to unconjugated IgE in CFA, suggesting that tolerance exists at the level of T cells. The present study...
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ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 1988
ISSN: 0022-1007,1540-9538
DOI: 10.1084/jem.168.2.713